منابع مشابه
LC-MS and LC-MS/MS studies of incorporation of 34SO3 into glycosaminoglycan chains by sulfotransferases.
The specificities of glycosaminoglycan (GAG) modification enzymes, particularly sulfotransferases, and the locations and concentrations of these enzymes in the Golgi apparatus give rise to the mature GAG polysaccharides that bind protein ligands. We studied the substrate specificities of sulfotransferases with a stable isotopically labeled donor substrate, 3'-phosphoadenosine-5'-phosphosulfate....
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A rapid, robust, sensitive and specific LC-MS/MS assay using the AB SCIEX QTRAP 6500 system has been developed for the simultaneous detection of all major forms of vitamin B complex. The method detects all currently used forms of vitamin B6 and vitamin B3 in infant formula and includes vitamin B12. The sample preparation allows the same extract to be used for Vitamin C detection and the LC-MS/M...
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Aflatoxins (AFs) belong to a closely related group of secondary fungal metabolites. These mycotoxins are severely toxic metabolites produced mainly by Aspergillus flavus and A. parasiticus, and exposure to them can cause cancer in humans and livestock [1]. Based on epidemiological evidence, AFs have been classified as human liver carcinogens by the World Health Organization and by the U.S. Envi...
متن کاملLipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS
We present a method for the systematic identification of picogram quantities of new lipids in total extracts of tissues and fluids. It relies on the modularity of lipid structures and applies all-ions fragmentation LC-MS/MS and Arcadiate software to recognize individual modules originating from the same lipid precursor of known or assumed structure. In this way it alleviates the need to recogni...
متن کاملQuantitation of cyclic dinucleotides by reversed-phase LC-MS/MS
Cyclic dinucleotides such as bis-(3',5')-cyclic dimeric adenosine monophosphate (c-di-AMP) and bis-(3',5')-cyclic dimeric guanosine monophosphate (c-di-GMP) represent important second messengers in bacteria. Although their synthesis has not been described in plants so far, they may be involved in the regulation of bacterial phytopathogen-plant interactions as well as rhizobium plant symbiosis. ...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2016
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2015.246264